7-{4-[(1,3-Benzodioxol-5-yl)methyl]piperazin-1-yl}-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
نویسندگان
چکیده
منابع مشابه
1-Cyclopropyl-6-fluoro-7-(4-nitrosopiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
The title compound, C(17)H(17)FN(4)O(4), is a derivative of ciprofloxacin [1-cyclo-propyl-6-fluoro-4-oxo-7-(1-piperazin-yl)-1,4-dihydro-quinoline-3-carboxylic acid]. The crystal packing is stabilized by inter-molecular C-H⋯O hydrogen bonds together with π-π electron ring inter-actions [centroid-centroid separations between quinoline rings of 3.5864 (11) and 3.9339 (13) Å]. A strong intra-molecu...
متن کامل1-Ethyl-6-fluoro-7-(4-methylpiperazin-4-ium-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate hexahydrate
In the title compound, C(17)H(20)FN(3)O(3)·6H(2)O, the pefloxacin (pef) neutral zwitterion is accompanied by six water mol-ecules of hydration. An extensive network of O-H⋯O and N-H⋯O hydrogen bonds help to establish the crystal packing.
متن کامل7-{4-[(1,3-Benzodioxol-5-yl)methyl]piperazin-1-yl}-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
In the title structure, C(25)H(24)FN(3)O(5), a strong intra-molecular O-H⋯O hydrogen bond is present between the carb-oxy group at the 3-position and the carbonyl group at the 4-position. In the crystal, mol-ecules are held together by weak C-H⋯O, C-H⋯F and π-π [centroid-centroid distance 3.6080 (8) Å] inter-actions. The 1,4-dihydro-quinoline ring and cyclo-propyl group are not in the same plan...
متن کاملDiaquabis[1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylato]magnesium(II) hexahydrate
In the title compound, [Mg(C(16)H(17)FN(3)O(3))(2)(H(2)O)(2)]·6H(2)O, the Mg(2+) ion (site symmetry ) exhibits a distorted MgO(6) octa-hedral geometry defined by two O,O-bidentate 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazin-yl)-3-quinoline-carb-oxyl-ate (norf) anions and two water mol-ecules. In the crystal, O-H⋯O and O-H⋯N hydrogen bonds help to establish the packing.
متن کاملCrystal structure of 1-cyclopropyl-2-ethyl-5-fluoro-6- (4-methylpiperazin-1-yl)-1H-benzimidazole.
biological activities,1 and some of them are used as drugs.2,3 In previous studies,4,5 we reported on the synthesis and biological evaluation of 1,2,5(6)-trisubstituted benzimidazoles as antihistaminic and antimicrobial agents. The synthesis of ethyl 1-cyclopropyl-5-fluoro-6-(4-methylpiperazine-1-yl)-1H-benzimidazole-2-acetate (1) was performed according to reported methods.6,7 1-Cyclopropyl-2-...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2012
ISSN: 1600-5368
DOI: 10.1107/s1600536812028711